Effect of intravariceal sclerotherapy combined with esophageal mucosal sclerotherapy using small-volume sclerosant for cirrhotic patients with high variceal pressure

作     者：De-Run Kong Jin-Guang Wang Chen Chen Fang-Fang Yu Qiong Wu Jian-Ming Xu 

作者机构：Department of Gastroenterologythe First Affiliated Hospital of Anhui Medical University 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2015年第21卷第9期

页      面：2800-2806页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by Educational and Health Department of Anhui Province,No.KJ2010A158,No.KJ2012Z189 and No.2010B018 National Natural Science Foundation of China,No.81271736 

主　　题：Variceal bleeding Endoscopic variceal ligation End 

摘      要：AIM:To explore the effect of intravariceal-mucosal sclerotherapy using small dose of sclerosant on the recurrence of esophageal ***:We randomly assigned 38 cirrhotic patients with previous variceal bleeding and high variceal pressure( 15.2 mm Hg) to receive endoscopic variceal ligation(EVL) and combined intravariceal and esophageal mucosal sclerotherapy(combined group) using small-volume *** end-points of the study were rebleeding and recurrence of esophageal ***:During a median follow-up period of 16 mo,varices recurred in 1 patient in the combined group as compared with 7 patients in the EVL group(P =0.045).Rebleeding occurred in 3 patients in the EVL group as compared with 1 patient in the combined group(P=0.687).No patient died in the two *** significant differences were observed between the two groups with respect to serious adverse ***:Intravariceal-mucosal sclerotherapy using small dose of sclerosant is more effective than EVL in decreasing the incidence of variceal recurrence for cirrhotic patients.