Second to fourth digit ratio： a predictor of adult lung function

作     者：I-Nae Park Ho-Kee Yum Sang Chul Lee Jin Kyu Oh Tae Beom Kim 

作者机构：Department of Pulmonology Inje University Seoul Paik Hospital Seoul Korea Department of Urology Gachon University Gil Hospital Incheon Korea 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2014年第16卷第1期

页      面：140-145页

核心收录：

学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 1002[医学-临床医学] 082903[工学-林产化学加工工程] 07[理学] 08[工学] 0829[工学-林业工程] 09[农学] 0903[农学-农业资源与环境] 082201[工学-制浆造纸工程] 0822[工学-轻工技术与工程] 0713[理学-生态学] 

基　　金：supported by Inje University Research Grant 

主　　题：airway function digit ratio sex hormone 

摘      要：Sex and sex hormones play a major role in lung physiology. It has been proposed that the ratio of the second to fourth digits （digit ratio） is correlated with fetal sex hormones. We therefore hypothesized that digit ratio might help predict lung function. We investigated the relationship between digit ratio and pulmonary function test （PFT） findings. A total of 245 South Korean patients （162 male, 83 female） aged from 34 to 90 years who were hospitalized for urological surgery were prospectively enrolled. Before administering the PFTs, the lengths of the second and fourth digits of the right hand were measured by a single investigator using a digital Vernier caliper. In males （n = 162）, univariate and multivariate analysis using linear regression models showed that digit ratio was a significant predictive factor of forced vital capacity （FVC） and forced expiratory volume in I second （FEV1） （FVC： r = 0.156, P = 0.047; FEVI： r = 0.160, P = 0.042）. In male ever-smokers （n = 69）, lung functions （FVC and FEV1） were correlated with smoking exposure rather than digit ratio. In female never-smokers （n = 83）, lung functions （FEV1 and FEVI/FVC ratio） were positively correlated with digit ratio on univariate analysis （FEVI： r = 0.242, P = 0.027; FEVI/FVC ratio： r = 0.245, P = 0.026）. Patients with lower digit ratios tend to have decreased lung function. These results suggest that digit ratio is a predictor of airway function.