Prevalence, risk factors, clinical course, and outcome of acute kidney injury in Chinese intensive care units： a prospective cohort study
Prevalence, risk factors, clinical course, and outcome of acute kidney injury in Chinese intensive care units： a prospective cohort study作者机构：Department of Critical Care Medicine Fuxing Hospital Capital Medical University Beijing 100038 China Department of Critical Care Medicine Beijing Tongren HospitalCapital Medical University Beijing 100730 China Department of Emergency Medicine First Affiliated Hospital of Kunming Medical College Kunming Yunnan 650032 China Department of Critical Care Medicine Tongji Hospital Tongji Medical College Huazhong University of Science & TechnologyWuhan Hubei 430030 China Department of Critical Care Medicine Guangdong General HospitalGuangzhou Guangdong 510080 China Department of Emergency Medicine Ruijin Hospital Shanghai Jiao Tong University Shanghai 200025 China Department of Critical Care Medicine First Affiliated Hospital ofFuiian Medical University Fuzhou Fujian 350005 China Department of Critical Care Medicine Xiangya Hospital CentralSouth University Changsha Hunan 410008 China Department of Critical Care Medicine Qilu Hospital Shandong University Jinan Shandong 250012 China Department of Emergency and Critical Care Medicine The Second Hospital of Jilin University Changchun Jilin 130041 China Department of Critical Care Medicine Zhejiang Provincial People's Hospital Hangzhou Zhejiang 310014 China Department of Critical Care Medicine Hebei Medical University Fourth Hospital Shijiazhuang Hebei 050011 China Department of Critical Care Medicine Affiliated Hospital of Ningxia Medical University Yinchuan Ningxia 750004 China Department of Critical Care Medicine First Affiliated Hospital Chongqing Medical University Chongqing 400016 China Department of Critical Care Medicine Hainan Provincial People's Hospital Haikou Hainan 570311 China Department of Critical Care Medicine Affiliated Hospital of Inner Mongolia Medical College Huhhot Inner Mongolia 010050 China Department of Critical Care Medicine Peking University People's Hospital Beijing 100044 China Department of Critical Care Medicine West China Hospital Sichuan University Chengdu Sichuan 610041 China Department of Critical Care Medicine The First Affiliated Hospital of China Medical University Shenyang Liaoning 110001 China Department of Critical Care Medicine First Affiliated Hospital Xinjiang Medical University Urumqi Xinjiang 830054 China Department of Critical Care Medicine The First Affiliated Hospital Haerbin Medical University Haerbin Heilongjiang 150001 China Medical Intensive Care Unit Peking Union Medical College Hospital Beijing 100730 China
出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)
年 卷 期：2013年第126卷第23期
页 面：4409-4416页
核心收录：
学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 0817[工学-化学工程与技术] 08[工学] 09[农学] 0903[农学-农业资源与环境] 0713[理学-生态学]
基 金：the Beijing Municipal Science & Technology Commission (BSTC)
主 题：acute kidney injury intensive care units mortality prevalence risk factors
摘 要：Background Acute kidney injury （AKI） has been recognized as a major healthcare problem affecting millions of patients ***,epidemiologic data concerning AKI in China are still *** objectives of this study were to characterize AKI defined by RIFLE criteria,assess the association with hospital mortality,and evaluate the impact of AKI in the context of other risk *** This prospective multicenter observational study enrolled 3,063 consecutive patients from 1 July 2009 to 31 August 2009 in 22 ICUs across China s *** excluded patients who were admitted for less than 24 hours （n=1623）,younger than 18 years （n=127）,receiving chronic hemodialysis （n=29）,receiving renal transplantation （n=1） and unknown reasons （n=28）.There were 1255 patients in the final *** was diagnosed and classified according to RIFLE *** There were 396 patients （31.6％） who had AKI,with RIFLE maximum class R,I,and F in 126 （10.0％）,91 （7.3％）,and 179 （14.3％） patients,*** function deteriorated in 206 patients （16.4％）.In comparison with non AKI patients,patients in the risk class on ICU admission were more likely to progress to the injury class （odds ratio （OR） 3.564,95％ confidence interval （CI） 1.706-7.443,P =0.001],while patients in the risk class （OR 5.215,95％ CI 2.798-9.719,P 0.001） and injury class （OR 13.316,95％ CI 7.507-23.622,P 0.001） had a significantly higher probability of deteriorating into failure *** adjusted hazard ratios for 90-day mortality were 1.884 for the risk group,3.401 for the injury group,and 5.306 for the failure *** The prevalence of AKI was high among critically ill patients in Chinese *** comparison with non-AKI patients,patients with RIFLE class R or class I on ICU admission were more susceptibility to progression to class I or class *** RIFLE criteria were robust and correlated well with clinical deterioration and mortality.
维普期刊数据库