Carcinosarcoma of the stomach:A case report and review of the literature

作     者：Tomislav Randjelovic Branka Filipovic Darko Babic Vesna Cemerikic Branislav Filipovic 

作者机构：Department of Gastrointestinal SurgeryClinical and Hospital Center "Bezanijska Kosa" BelgradeSerbia Department of Gastroenterohepatology Clinical and Hospital Center "Bezanijska Kosa" Belgrade 11080Serbia Department of PathologyClinical and Hospital Center "Bezanijska Kosa" Belgrade 11080Serbia Laboratory for Histopathological and Cytological Diagnostics "Histolab" Belgrade 11080Serbia Institute of AnatomySchool of MedicineUniversity of BelgradeBelgrade 11080Serbia 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2007年第13卷第41期

页      面：5533-5536页

核心收录：

学科分类：0501[文学-中国语言文学] 05[文学] 

主　　题：Carcinosarcoma Histochemistry Pathology Stomach 

摘      要：Carcinosarcomas are rare,malignant,biphasic tumors. We report the case of a 62-year-old man with gastric carcinosarcoma,along with its clinical,macroscopic and histopathological features. Macroscopically,a specimen of deformed stomach was obtained that measured 200 mm×150 mm×100 mm. A 150 mm×100 mm× 50 mm exophytic tumoral mass (Borrmann typeⅠ) was found,which involved the posterior wall from the cardia to the antrum. Histopathologically,a mixed type of malignancy was revealed: an adenocarcinoma with intestinal metaplasia,with interposed fascicles of fusiform atypical cells and numerous large,rounded and oval cells. The tumor showed positive histochemistry for cytokeratin 18,epithelial membrane antigen,carcinoembryonic antigen,chromogranin A and vimentin. Liver metastases were diagnosed 8 mo postoperatively,and the patient died 4 mo later. A review of the available literature is also presented.