Clinical effects and complications of TIPS for portal hypertension due to cirrhosis:A single center

作     者：Jian-Ping Qin Ming-De Jiang Wen Tang Xiao-Ling Wu Xin Yao Wei-Zheng Zeng Hui Xu Qian-Wen He Ming Gu 

作者机构：Department of DigestionChengdu Military General Hospital Department of Radiology Chengdu Military General Hospital 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2013年第19卷第44期

页      面：8085-8092页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by The grant from Chengdu Military General Hospital No.424121HK 

主　　题：Transjugular intrahepatic portosystemic shunt Cirrhosis Portal hypertension Therapeutic effect Complication 

摘      要：AIM:To determine the clinical effects and complications of transjugular intrahepatic portosystemic shunt(TIPS)for portal hypertension due to ***:Two hundred and eighty patients with portal hypertension due to cirrhosis who underwent TIPS were retrospectively *** trunk pressure was measured before and after *** changes in hemodynamics and the condition of the stent were assessed by ultrasound and the esophageal and fundic veins observed ***:The success rate of TIPS was 99.3%.The portal trunk pressure was 26.8±3.6 cmH2O after surgery and 46.5±3.4 cmH2O before surgery(P0.01).The velocity of blood flow in the portal vein *** internal diameters of the portal and splenic veins were *** short-term hemostasis rate was100%.Esophageal varices disappeared completely in68%of patients and were obviously reduced in 32%.Varices of the stomach fundus disappeared completely in 80%and were obviously reduced in 20%of *** disappeared in 62%,were markedly reduced in 24%,but were still apparent in 14%of *** total effective rate of ascites reduction was 86%.Hydrothorax completely disappeared in 100%of *** incidence of post-operative stent stenosis was 24%at 12 mo and 34%at 24 *** incidence of post-operative hepatic encephalopathy was 12%at3 mo,17%at 6 mo and 19%at 12 *** incidence of post-operative recurrent hemorrhage was 9%at 12mo,19%at 24 mo and 35%at 36 *** cumulative survival rate was 86%at 12 mo,81%at 24 mo,75%at 36 mo,57%at 48 mo and 45%at 60 ***:TIPS can effectively lower portal hypertension due to *** is significantly effective for hemorrhage of the digestive tract due to rupture of esophageal and fundic veins and for ascites and hydrothorax caused by portal hypertension.