Tumor-targeted niosome as novel carrier for intravenous administration of tocotrienol

作     者：Ju-Yen Fu Doryn Meam Yee Tan Hui Meng Er Yu Sui Chen Kalanithi Nesaretnam 

作者机构：Malaysian Palm Oil BoardBandar Baru BangiSelangor 43000Malaysia International Medical UniversityBukit JalilKuala Lumpur 57000Malaysia 

出 版 物：《Asian Journal of Pharmaceutical Sciences》 (亚洲药物制剂科学（英文）)

年 卷 期：2016年第11卷第1期

页      面：79-80页

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：Malaysian Palm Oil Board International Medical University, IMU 

主　　题：Tocotrienol Niosome Tumour-targeted Breast cancer 

摘      要：Tocotrienol(T3),the unsaturated form of vitamin E,has gained global attention due to its potent anticancer effects against a wide range of *** abundantly in palm oil[1],T3was reported to exhibit their anti-cancer properties via various pathways including anti-proliferative,anti-angiogenesis,antiinflammatory,apoptosis and improvement of immunological function[2].However,the lack of tumor specificity and rapid body clearance have restricted the clinical applications of T3[3].