Health care-associated hepatitis C virus infection

作     者：Bruno Pozzetto Meriam Memmi Olivier Garraud Xavier Roblin Philippe Berthelot 

作者机构：Groupe Immunité des Muqueuses et Agents Pathogènes (GIMAP EA3064)Faculty of Medecine of Saint-EtienneUniversity of Lyon42023 Saint-EtienneFrance Department of Infectious Agents and HygieneUniversity-Hospital of Saint-Etienne42055 Saint-EtienneFrance Institut National de la Transfusion Sanguine75015 ParisFrance Department of Gastroenterology and HepatologyUniversity-Hospital of Saint-Etienne42055 Saint-EtienneFrance Department of Infectious Diseases and HygieneUniversity-Hospital of Saint-Etienne42055 Saint-EtienneFrance 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第46期

页      面：17265-17278页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Hepatitis C virus Health care-associated infection Health care worker Standard precautions Hemodialysis Unsafe injections Occupational exposure Antiviral drugs 

摘      要：Hepatitis C virus(HCV)is a blood-borne pathogen that has a worldwide distribution and infects millions of ***-associated HCV infections represented a huge part of hepatitis C burden in the past via contaminated blood and unsafe injections and continue to be a serious problem of public *** present review proposes a panorama of health care-associated HCV infections via the three mode of contamination that have been identified:(1)infected patient to non-infected patient;(2)infected patient to non-infected health careworker(HCW);and(3)infected HCW to non infected *** each condition,the circumstances of contamination are described together with the means to prevent *** a whole,the more important risk is represented by unsafe practices regarding injections,notably with the improper use of multidose vials used for multiple *** questions of occupational exposures and infected HCWs are also *** terms of prevention and surveillance,the main arm for combating care-associated HCV infections is the implementation of standard precautions in all the fields of cares,with training programs and audits to verify their good *** must be sensitized to the risk of blood-borne pathogens,notably by the use of safety devices for injections and good hygiene practices in the operating theatre and in all the invasive *** providers performing exposed-prone procedures must monitor their HCV serology regularly in order to detect early any primary infection and to treat it without *** the need to stay vigilant because HCV infection is often a hidden risk,it can be hoped that the number of people infected by HCV via health care will decrease very significantly in the next years.