Environmental noise alters gastric myoelectrical activity:Effect of age

作     者：James S Castle Mark R Warner Mark A Korsten 

作者机构：Medical Program and Audiology Service James J Peters VA Medical Center Bronx NY and Mount Sinai School of Medicine New York United States 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2007年第13卷第3期

页      面：403-407页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Noise, Acoustic stress, Gastric myoelectrical activity Electrogastmgram Autonomic nervous system 

摘      要：AIM: To evaluate the effect of age and acoustic stress on gastric myoelectrical activity (GMA) and autonomic nervous system function. METHODS: Twenty-one male subjects (age range 22-71 years, mean 44 years) were recruited and exposed, in random order, to three auditory stimuli (Hospital noise, conversation babble and traffic noise) after a 20-min baseline. All periods lasted 20 min and were interspersed with a 10 min of recovery. GMA was obtained using a Synectics Microdigitrapper. Autonomic nerve function was assessed by monitoring blood pressure and heart rate using an automatic recording device. RESULTS: Dominant power tended to decrease with increase of age (P 0.05). The overall percentage of three cycle per minute (CPM) activity decreased during exposure to hospital noise (12.0%, P 0.05), traffic noise (13.9%, P 0.05), and conversation babble (7.1%). The subjects in the younger group ( 50 years) showed a consistent reduction in the percentage of 3 CPM activity during hospital noise (22.9%, P 0.05), traffic noise (19.0%, P 0.05), and conversation babble (15.5%). These observations were accompanied by a significant increase in bradygastria: hospital noise (P 0.05) and traffic noise (P 0.05). In contrast, the subjects over 50 years of age did not exhibit a significant decrease in 3 CPM activity. Regardless of age, noise did not alter blood pressure or heart rate. CONCLUSION: GMA changes with age. Loud noise can alter GMA, especially in younger individuals. Our data indicate that even short-term exposure to noise may alter the contractility of the stomach.