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Neoadjuvant therapy for esophageal cancer

Neoadjuvant therapy for esophageal cancer

作     者:Rachit D Shah Anthony D Cassano James P Neifeld 

作者机构:De-partment of Surgery Virginia Commonwealth University School of Medicine Richmond VA 23298-0068 United States 

出 版 物:《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志(英文版)(电子版))

年 卷 期:2014年第6卷第10期

页      面:403-406页

核心收录:

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主  题:Neoadjuvant therapy Esophageal cancer Esophagectomy Chemotherapy 

摘      要:Esophageal cancer is increasing in incidence more than any other visceral malignancy in North America. Adenocarcinoma has become the most common cell type. Surgery remains the primary treatment modality for locoregional disease. Overall survival with surgery alone has been dismal, with metastatic disease the primary mode of treatment failure after an R0 surgical resection. Cure rates with chemotherapy or radiation therapy alone have been disappointing as well. For these reasons, over the last decade multi-modality treatment has gained increasing acceptance as the standard of care. This review examines the present data and role of neoadjuvant treatment using chemotherapy and radiation therapy followed by surgery for the treatment of esophageal cancer.

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