Bioinformatics analysis of potential essential genes that response to the high intraocular pressure on astrocyte due to glaucoma
Bioinformatics analysis of potential essential genes that response to the high intraocular pressure on astrocyte due to glaucoma作者机构：Department of Ophthalmology China Medical UniversityShengjing Hospital Department of Orthopedics China Medical UniversityShengjing Hospital
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2015年第8卷第2期
页 面：395-398页
核心收录：
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题：high intraocular pressure microarray glaucoma astrocytes
摘 要：AIM: To study the gene expression response and predict the network in cell due to pressure effects on optic nerve injury of ***: We used glaucoma related microarray data in public database [Gene Expression Omnibus(GEO)] to explore the potential gene expression changes as well as correspondent biological process alterations due to increased pressure in astrocytes during glaucoma ***: A total of six genes were identified to be related with pressure increasing. Through the annotation and network analysis, we found these genes might be involved in cell morphological remodeling, angiogenesis,mismatch ***: Increasing pressure in glaucoma on astrocytes might cause gene expression alterations,which might induce some cellular responses changes.
维普期刊数据库
