Endoscopic scoring of late gastrointestinal mucosal damage after adjuvant radiochemotherapy

作     者：Resat Dabak Oya Uygur-Bayramicli Cengiz Gemici Dilek Yavuzer Mehmet Sargin Mehmet Yildirim 

作者机构：Department of Family MedicineKartal State HospitalKartalstanbulTurkey Department of GastroenterologyKartal State HospitalKartalstanbulTurkey Department of Radiation OncologyKartal State HospitalKartalstanbulTurkey Department of PathologyKartal State HospitalKartalstanbulTurkey Department of General SurgeryKartal State HospitalKartalstanbulTurkey 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2006年第12卷第27期

页      面：4411-4415页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Radiochemotherapy Gastric cancer Endoscopy Gastrointestinal rnucositis 

摘      要：AIM： To evaluate late effects of chemoradiation on gastrointestinal mucosa with an endoscopic scoring system and compare it to a clinical scoring system. METHODS： Twenty-four patients going to receive chemoradiation after gastric surgery underwent endoscopy four wk after surgery and one year after the chemoradiation finished. Upper gastrointestinal findings were recorded according to a system proposed by World Organisation for Digestive Endoscopy （OMED） and clinical scoring was done with RTOG-EORTC radiation morbidity scoring systems. RESULTS： There was no significant endoscopic difference in gastric and intestinal mucosa after chemoradiation （P 〉 0.05） and there was no association between endoscopic scores and clinical scores. Endoscopic changes were minimal. CONCLUSION： Late effects after chemoradiation in operated patients with gastric cancers can be evaluated with an endoscopic scoring system objectively and this system is superior to clinical scoring systems.