Intravascular ultrasound-based analysis of factors affecting minimum lumen area in coronary artery intermediate lesions

作     者：Jian LIU Ying ZHANG Wei-Min WANG Zhao WANG Qi LI Chuan-Fen LIU Yu-Liang MA Ming-Yu LU Hong ZHAO 

作者机构：Department of Cardiology Peking University People's Hospital Beijing China 

出 版 物：《Journal of Geriatric Cardiology》 (老年心脏病学杂志（英文版）)

年 卷 期：2016年第13卷第2期

页      面：169-174页

核心收录：

学科分类：02[经济学] 082802[工学-农业水土工程] 07[理学] 08[工学] 09[农学] 070103[理学-概率论与数理统计] 0202[经济学-应用经济学] 020208[经济学-统计学] 0828[工学-农业工程] 0815[工学-水利工程] 0903[农学-农业资源与环境] 0714[理学-统计学（可授理学、经济学学位）] 0701[理学-数学] 

主　　题：Intermediate lesions Intravascular ultrasound Predictive model Risk factors 

摘      要：Objective To identify clinical characteristics associated with the minimum lumen area （MLA） of proximal or middle intermediate lesions in the left anterior descending （LAD） artery, and to develop a model to predict MLA. Methods We retrospectively analyzed demographic data, medical history, and intravascular ultrasound findings for 90 patients with intermediate lesions in the LAD artery. Linear regression was used to identify factors affecting MLA, and multiple regression was used to develop a model for predicting MLA. Results Age, number of lesions, and diabetes mellitus correlated significantly with MLA of proximal or middle intermediate lesions. A regression model for predicting MLA （mm2） was derived from the data： 7.00 - 0.05 × （age） - 0.50 × （number of lesions）. A cut-off value of 3.1 mm2 was proposed for deciding when to perform percutaneous coronary intervention. Conclusion This model for predicting MLA of proximal or middle intermediate lesions in the LAD artery showed high accuracy, sensitivity, and specificity, indicating good diagnostic potential.