Effect of Selenium Poisoning on Immune Function and Oxygen Free Radicals in Erythrocyte of Pig
Effect of Selenium Poisoning on Immune Function and Oxygen Free Radicals in Erythrocyte of Pig作者机构：School of Basic Medical Xianning College Xianning 437100 China College of Animal medical Huazhong Agricultural University Wuhan 430070 China
出 版 物：《Animal Husbandry and Feed Science》 (动物与饲料科学（英文版）)
年 卷 期：2009年第1卷第8期
页 面：25-26,29页
学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 0905[农学-畜牧学] 08[工学] 09[农学] 0903[农学-农业资源与环境] 0713[理学-生态学]
主 题：Selenium poisoning Pig Erythrocyte immune function Oxygen free radicals
摘 要：[ Objective] This study was to investigate the effect of selenium（Se） on immune function and oxygen free radicals in erythrocyte of pig. [ Method] Fifteen weanling Landrace piglets as experimental animals were divided into three groups, two testing groups and one control group. For each group, Se content in whole blood, immune function of erythrocytes, activity of whole blood glutathione peroxidase（GSH-Px）, activity of blood plasma superoxide dismutase（SOD）, and blood plasma malondialdehyde（MDA） content were determined. [ Result] Compared with the control group, Se content in whole blood and blood plasma MDA content increased remarkably, while whole blood GSH-Px activity and blood plasma SOD activity decreased; RBC-C1 RR assumed a rise-fall trend, and RBC-ICR showed no obvious change. [Condusion] Se poisoning can reduce the activity of antioxidant enzymes, disturb the balance of oxygen free radicals metabolism, thereby inducing erythrooyte immune function in piglets.
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