风湿性疾病患者施行LASIK术:一项先导研究

作     者：AlióJ.L Artola A Belda J.I. 王静波 

作者机构：Dr. Instituto Oftalmológico de Alicante Edificio Vissum Avda. Denia s/n 03016 Alicante Spain 

出 版 物：《世界核心医学期刊文摘(眼科学分册)》 (Digest of the World Core Medical Journals)

年 卷 期：2006年第3期

页      面：47-48页

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

主　　题：LASIK 风湿性疾病 风湿病 结缔组织疾病 角膜曲率计 角膜曲率仪 患者 

摘      要：Purpose: To investigate the safety of LASIK in patients with a known history of controlled rheumatic diseases. Design: Retrospective consecutive observational clinical study. Participants: Forty-two eyes (22 patients) known to have had a history of rheumatic diseases underwent *** patients had a history of controlled rheumatic diseases, including rheumatoid arthritis, systemic lupus erythematosus, dermatomyositis, scleroderma, ankylosing spondylitis, psoriatic arthritis, inflammatory bowel disease, arthritis, or Behet’s disease. Methods: Assessments were made preoperatively and at 1, 3, and 6 months postoperatively and included visual acuity (VA), refraction, keratometric readings, slit-lamp biomicroscopy, and corneal topography. All the patients underwent LASIK. Postoperative treatment included a topical steroid-antibiotic combination. Main Outcome Measures: Visual acuity, refraction, keratometric readings, and slit-lamp biomicroscopy findings at 1, 3, and 6 months postoperatively. Results: LASIK was performed uneventfully on all patients. The mean pre-LASIK spherical equivalent (SE)-was-5.39±2.25, and the sixth month postoperative SE was-0.15±0.38 diopters (D) (P 0.001). Uncorrected VA 6 months after the LASIK procedure was 20/25. Enhancement procedures were performed in 6 of 42 eyes (14.3%) at variable times after the primary procedure. Postoperative follow-up showed development of a moderate degree of dry eye syndrome in 4 eyes (9.5%). Corneal haze, melting, flap, or interface complications were not observed in any of the study eyes. Conclusions : In this small series, we found good outcomes when correcting refractive errors using LASIK in selected patients with controlled rheumatic diseases. In this series, a favorable postoperative visual outcome was obtained with no operative or postoperative vision-threatening complications.