Primary hepatic neuroendocrine tumor with a suspicious pulmonary nodule:A case report and literature review
作者机构：Department of NursingThe Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Burns and Wound Care CenterThe Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Nursing PathologyThe Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of SurgeryThe Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Key Laboratory of Cancer Prevention and InterventionChina National Ministry of EducationCancer InstituteThe Second Affiliated HospitalZhejiang University School of MedicineHangzhou 310009Zhejiang ProvinceChina Department of Cancer CenterZhejiang UniversityHangzhou 310000Zhejiang ProvinceChina Harvard T.H.Chan School of Public HealthHarvard UniversityCambridgeMA 02138United States
出 版 物：《World Journal of Clinical Oncology》 (世界临床肿瘤学杂志(英文))
年 卷 期：2025年第16卷第3期
页 面：123-133页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Primary hepatic neuroendocrine tumors Pulmonary nodule Neuroendocrine neoplasms Liver Surgical resection Case report
摘 要：BACKGROUND Primary hepatic neuroendocrine tumors(PHNETs)are extremely rare tumors originating from neuroendocrine *** to lack of neuroendocrine symptoms and specific radiographic characteristics,PHNETs are challenging to differentiate from other liver *** SUMMARY This case involved a 67-year-old male who was admitted with a discovered hepatic mass and a suspicious lung *** hepatic carcinoma was initially speculated based on the characteristic magnetic resonance imaging *** patient underwent a laparoscopic right partial hepatectomy,and subsequent immunohistochemical examination revealed a *** exclude other potential origins,a positron emission tomography-computed tomography scan and gastrointestinal endoscopy were performed,leading to a final diagnosis of *** we conducted a literature review using the PubMed database,identifying 99 articles and 317 cases related to *** characteristics,diagnostic methods,and treatment of PHNETs have been ***,we elaborate on the presumed origins,pathological grades,clinical features,diagnosed methods,and treatments associated with *** The diagnosis of PHNETs was primarily an exclusionary process.A definitive diagnosis of PHNETs relied mainly on immunohistochemical markers(chromogranin A,synaptophysin,and cluster of differentiation 56)and exclusion of primary foci in other *** surgery was the preferred treatment for early-stage tumors.
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