Platelet rich plasma and anterior cruciate ligament repair:A new frontier,or a short term adjunct

作     者：Saran Singh Gill Giulia Cenci Susanna Falcinelli Fabrizio Marzano Bruno Carriero Nicola Filippi Valerio Pace 

作者机构：Faculty of MedicineImperial College LondonLondon SW72AZUnited Kingdom Department of Trauma and OrthopaedicsAOSP TerniTerni 05100UmbriaItaly Department of Trauma and OrtopaedicsOspedale Degli InfermiFaenza 48018Italy Orthopaedic and Traumatology UnitDepartment of Knee SurgeryASL ViterboViterbo 01100Italy 

出 版 物：《World Journal of Orthopedics》 (世界骨科杂志(英文))

年 卷 期：2025年第16卷第1期

页      面：12-17页

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Anterior cruciate ligament Anterior cruciate ligament repair Anterior cruciate ligament rupture Platelet rich plasma New frontier 

摘      要：Platelet rich plasma(PRP)is an autologous blood product rich in platelets,showing promise in reducing inflammation and accelerating *** extensively utilized in plastic surgery,dermatology,and osteoarthritis treatment,its application in anterior cruciate ligament(ACL)injuries is *** article examines PRP s potential in ACL reconstruction(ACLR),exploring its history,current usage,controversies and future *** has demonstrated significant early benefits in ligamentisation and vascularisation post-ACLR,though its long-term efficacy is *** suggest that PRP may serve as both an adjunct therapy in ACLR to enhance initial healing and reduce postoperative complications,and as a non-surgical alternative for small ACL *** these promising findings,outcome variability necessitates further high-quality research to optimize PRP formulations and determine its most effective *** exploration of PRP as a treatment modality in ACLR offers promising but varied *** holds considerable promise as both an adjunct and alternative to traditional *** article underscores the need for targeted research to fully realize PRP s therapeutic potential in ACL treatment,aiming to inform future studies and clinical *** understanding PRP s mechanisms of efficacy and identifying the most beneficial patient populations,PRP could significantly impact orthopaedics and sports medicine,improving recovery pathways and patient outcomes.