Potential clinical treatment for Ebola pandemic

作     者：ZHONG Ying XU Jun LI TaiSheng YU XueZhong SHENG MiaoMiao 

作者机构：State Key Laboratory of Medical Molecular Biology Institute of Basic Medical Sciences Chinese Academy of Medical Sciences Department of Biochemistry and Molecular Biology Peking Union Medical College Tsinghua University Department of Emergency Medicine Peking Union Medical Collage Hospital Peking Union Medical College Chinese Academy of Medical Sciences Department of Infectious Diseases Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Laboratory of Molecular Genetics of Aging & Tumor Medical Faculty Kunming University of Science and Technology Chenggong Campus 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2014年第57卷第10期

页      面：982-984页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：埃博拉病毒 临床治疗 刚果民主共和国 扎伊尔 死亡人数 感染病例 象牙海岸 传染病 

摘      要：West African countries are currently suffering the most severe pandemic of Ebola virus disease ever recorded, with 4269 human cases and 2288 deaths （through 6 September 2014）, and the number of cases in the current outbreak exceeds the number from all previous outbreaks combined. Ebola virus disease was first described in 1976 originating from the Ebola River in the Democratic Republic of the Congo. Five Ebola viruses have been reported to cause Ebola virus pandemics, including Zaire Ebola virus, Sudan Ebola virus, Ivory Coast Ebola virus, Reston Ebola virus and Bundibugyo Ebola virus. The Zaire Ebola virus is the most deadly with a fatality rate up to 90%. Unfortunately, the current outbreak in the West African countries is caused by the Zaire Ebola virus, and no specific treatment for the disease is yet available.