Current status of FAP-directed cancer theranostics:a bibliometric analysis
作者机构：Department of Nuclear Medicine and Minnan PET Center Xiamen Key Laboratory of Development and Translation of Radiopharmaceuticals the First Affiliated Hospital of Xiamen University School of Medicine Xiamen University National Institute for Data Science in Health and Medicine Department of Electronic Science Intelligent Medical Imaging R & D Center Fujian Provincial Key Laboratory of Plasma and Magnetic Resonance Xiamen University Department of Cardiology the First Affiliated Hospital of Xiamen University School of Medicine Xiamen University Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth Materials Haixi Institute Chinese Academy of Sciences
出 版 物：《Biophysics Reports》 (生物物理学报)
年 卷 期：2024年第10卷第6期
页 面：388-402页
核心收录：
学科分类：1205[管理学-图书情报与档案管理] 12[管理学] 1002[医学-临床医学] 100214[医学-肿瘤学] 120502[管理学-情报学] 10[医学]
基 金：supported by the National Natural Science Foundation of China (82071961) Fujian Research and Training Grants for Young and Middle-aged Leaders in Healthcare, Key Scientific Research Program for Yong Scholars in Fujian (2021ZQNZD016) Fujian Natural Science Foundation for Distinguished Yong Scholars (2022D005)
主 题：Cancer FAPI Fibroblast activation protein PET/CT Radionuclide Bibliometric analysis
摘 要：Fibroblast activation protein（FAP） is a key molecule in the field of oncology, with significant impacts on tumor diagnosis and treatment. Importantly, it has paved the way for the development of radiotracers for quinoline-based FAP inhibitors（FAPIs）, which are currently among the most promising radiotracers for PET imaging in cancer. We performed a bibliometric analysis of scientific publications related to FAP and FAPI-based radiotracers, which included the quantification and visualization of current research trends and prospects based on various bibliometric indicators. In our survey of FAP-related studies in the Web of Science Core Collection databases, R and VOSviewer were used for visualization and bibliometric analyses based on country, institute, author, journal, and keywords. We also examined the methodology, radionuclide type, imaging instruments, and major diseases associated with studies on FAPI-based radiotracers. The results revealed 2,664 FAP-related publications from 1992 to the present. Germany, the USA, and China dominated paper publications, multinational collaborations,and societal impacts on FAP research. Southwest Medical University was the most productive institute,while Haberkorn Uwe authored the most cited papers and the highest H-index. The European Journal of Nuclear Medicine and Molecular Imaging and the Journal of Nuclear Medicine were the most influential periodicals. Keywords FAP, 68Ga-FAPI, and PET/CT emerged as the most significant in this *** study may help elucidate current research trends, hotspots, and directions for future research.
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