Influence of gut bacteria on type 2 diabetes:Mechanisms and therapeutic strategy

作     者：Xue Wen Lu-Ming Qi Kui Zhao 

作者机构：College of Health and RehabilitationChengdu University of Traditional Chinese MedicineChengdu 610000Sichuan ProvinceChina College of Materials and Chemical EngineeringSouthwest Forestry UniversityKunming 650224Yunnan ProvinceChina 

出 版 物：《World Journal of Diabetes》 (世界糖尿病杂志（英文）)

年 卷 期：2025年第16卷第1期

页      面：27-33页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by"Caiyun Postdoctoral Program"of Innovation Project 2023 

主　　题：Type 2 diabetes Intestinal microbiome Intestinal axis Biological pathways Treatment Short-chain fatty acids 

摘      要：The onset and progression of type 2 diabetes mellitus(T2DM)are strongly associated with imbalances in gut bacteria,making the gut microbiome a new potential therapeutic *** commentary examines the recent publication in World Journal of *** article explores the association between T2DM and gut microbiota,with a focus on the pathophysiological changes related to *** proposes innovative microbiome-targeted therapeutic strategies and evaluates the challenges and future directions of such *** editorial summarizes the key points of their discussion of the role of the gut microbiome in T2DM and elaborates on the influence of specific gut microbial species on the disease through the host–microbiota metabolic *** provides new insights for future research on gut-microbiota-based interventions for T2DM.