Prevalence of Helicobacter pylori infection in China from 2014-2023:A systematic review and meta-analysis
作者机构：Department of Acquired Immune Deficiency Syndrome Treatment and Research CenterThe First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina The First Clinical Medical SchoolHenan University of Chinese MedicineZhengzhou 450046Henan ProvinceChina Department of SpleenStomachLiver and GallbladderThe First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina Henan Key Laboratory of Viral Diseases Prevention and Treatment of Chinese MedicineHenan University of Chinese MedicineZhengzhou 450000Henan ProvinceChina
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文）)
年 卷 期：2024年第30卷第43期
页 面：4636-4656页
核心收录：
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金：Supported by The Zhongyuan Famous Doctor,No.ZYYCYU202012119 Scientific Research Special Project of Traditional Chinese Medicine in Henan Province,No.2024ZY2004 Scientific Research Special Project of the National TCM Inheritance and Innovation Center of Henan Provincial Health Commission,No.2023ZXZX1093
主 题：Helicobacter pylori Meta-analysis Prevalence Epidemiology China
摘 要：BACKGROUND Helicobacter pylori(***)stands as the predominant infectious agent linked to the onset of gastritis,peptic ulcer diseases,and gastric cancer(GC).Identified as the exclusive bacterial factor associated with the onset of GC,it is classified as a group 1 carcinogen by the World Health *** elimination of *** plays a crucial role in the primary prevention of *** the prevalence has declined in recent decades,*** infection is still highly prevalent in China,accounting for a significant part of the disease burden of ***,updated prevalence information for *** infection,especially regional and demographic variations in China,is an important basis for the design of targeted strategies that will be effective for the prevention of GC and application of policies for *** *** To methodically evaluate the occurrence of *** infection throughout China and establish a reference point for subsequent *** A systematic review and meta-analysis was conducted following established guidelines,as detailed in our methodology *** Our review synthesized data from 152 studies,covering a sample of 763827 individuals,314423 of whom were infected with *** evaluated infection rates in China s Mainland and the combined prevalence of *** was 42.8%(95%CI:40.7-44.9).Subgroup analysis indicated the highest prevalence in Northwest China at 51.3%(95%CI:45.6-56.9),and in Qinghai Province,the prevalence reached 60.2%(95%CI:46.5-73.9).The urea breath test,which recorded the highest infection rate,showed a prevalence of 43.7%(95%CI:41.4-46.0).No notable differences in infection rates were observed between ***,the prevalence among the elderly was significantly higher at 44.5%(95%CI:41.9-47.1),compared to children,who showed a prevalence of 27.5%(95%CI:19.58-34.7).CONCLUSION Between 2014 and 2023,the prevalence of *** infection in China decreased to 42.8%,down from the previous d
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