Does N ratio affect survival in D1 and D2 lymph node dissection for gastric cancer?

作     者：Ibrahim Sakcak Baris Dogu Yildiz Fatih Mehmet Avsar Saadet Akturan Kemal Kilic Erdal Cosgun Enver O Hamamci 

作者机构：Department of 6th General SurgeryNumune Teaching and Research Hospital06100 SihhiyeAnkaraTurkey Department of 6th General SurgeryNumune Teaching and Research Hospital06100 SihhiyeAnkara Turkey Kafkas University Faculty of Medicine Chief of Surgery36000 KarsTurkey Department of General SurgeryEtlik Teaching and Research Hospital06010 AnkaraTurkey Kafkas University Faculty of MedicineGeneral Surgery Department36000 KarsTurkey Department of StatisticsHacettepe University Faculty of Medicine06100 SihhiyeAnkaraTurkey 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2011年第17卷第35期

页      面：4007-4012页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Gastric cancer Lymph node dissection Node ratio Tumor nodule metastasis 

摘      要：AIM:To identify whether there could have been changes in survival if lymph node ratio (N ratio) had been ***:We assessed 334 gastric adenocarcinoma cases retrospectively between 2001 and *** hundred and sixteen patients out of 334 were included in the *** were grouped according to disection1 (D1) or dissection 2 (D2) *** compared the estimated survival and actual survival determined by Pathologic nodes (pN) class and N ratio,and SPSS 15.0 software was used for statistical ***:Ninety-six (44.4%) patients underwent D1 dissection and 120 (55.6%) had D2 *** groups were evaluated,23 (24.0%) patients in D1 and 21 (17.5%) in D2 had stage migration (P=0.001).When both D1 and D2 groups were evaluated for number of pathological lymph nodes,despite the fact that there was no difference in N ratio between D1 and D2 groups,a statistically significant difference was found between them with regard to pN1 and pN2 groups (P=0.047,P=0.044 respectively).In D1,pN0 had the longest survival while pN3 had the *** D2,pN0 had the longest survival whereas pN3 had the shortest ***:N ratio is an accurate staging system for defining prognosis and treatment plan,thus decreasing methodological errors in gastric cancer staging.