Region stepwise reconstruction method based on two source–detector-separation groups for reconstructing background optical properties of two-layered slab sample

作     者：刘明 贾梦宇 赵会娟 高峰 

作者机构：College of Precision Instrument and Optoelectronics Engineering Tianjin University Tianjin Key Laboratory of Biomedical Detecting Techniques and Instruments 

出 版 物：《Chinese Optics Letters》 (中国光学快报（英文版）)

年 卷 期：2014年第12卷第11期

页      面：75-80页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 08[工学] 

基　　金：supported by the National Natural Science Foundation of China(Nos.81271618 and 81371602) the Tianjin Municipal Government of China(Nos.12JCQNJC09400 and 13JCZDJC28000) the Research Fund for the Doctoral Program of Higher Education of China(No.20120032110056) 

主　　题：Region stepwise reconstruction method based on two source detector-separation groups for reconstructing background optical properties of two-layered slab sample than 

摘      要：The accuracy of the background optical properties has a considerable effect on the quality of reconstructed images in near-infrared functional brain imaging based on continuous wave diffuse optical tomography（CW-DOT）. We propose a region stepwise reconstruction method in CW-DOT scheme for reconstructing the background absorption and reduced scattering coefficients of the two-layered slab sample with the known geometric information. According to the relation between the thickness of the top layer and source– detector separation, the conventional measurement data are divided into two groups and are employed to reconstruct the top and bottom background optical properties, respectively. The numerical simulation results demonstrate that the proposed method can reconstruct the background optical properties of two-layered slab sample effectively. The region-of-interest reconstruction results are better than those of the conventional simultaneous reconstruction method.