Impact of the next-generation sequencing data depth on various biological result inferences
Impact of the next-generation sequencing data depth on various biological result inferences作者机构：National Engineering Center for Biochip at Shanghai
出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)
年 卷 期：2013年第56卷第2期
页 面：104-109页
核心收录：
学科分类：0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种]
主 题：next-generation sequencing depth gene discovery gene expression structure variation next-generation sequencing depth gene discovery gene expression structure variation
摘 要：Next-generation sequencing(NGS) technologies have revolutionized the field of genomics and provided unprecedented opportunities for high-throughput analysis at the levels of genomics,transcriptomics and ***,the cost of NGS is still prohibitive for many *** is imperative to address the trade-off between the sequencing depth and *** this review,we will discuss the effects of sequencing depth on the detection of genes,quantification of gene expression and discovering of gene structural *** will provide readers information on choosing appropriate sequencing depth that best meet the needs of their particular project.
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