Mutation analysis of presenilin-1 gene in Alzheimer's disease patients and the effects of its mutation on expression of presenilin-1 and amyloid precursor protein
Mutation analysis of presenilin-1 gene in Alzheimer's disease patients and the effects of its mutation on expression of presenilin-1 and amyloid precursor protein作者机构:Dept Neurol2nd Affil HospZhejiang Univ
出 版 物:《China Medical Abstracts(Internal Medicine)》 (中国医学文摘(内科学分册(英文版))
年 卷 期:2013年第30卷第1期
页 面:64-64页
学科分类:1002[医学-临床医学] 100203[医学-老年医学] 10[医学]
主 题:amyloid mutation Mutation codon initiation mutant Initiation altered likely sequencing
摘 要:Objective To analyze the presenilin-1(PS-1) gene mutations in Alzheimer’s disease(AD) patients and investigate the influence of the initiation codon mutation on the mRNA expression of PS-1 and amyloid precursor