半胱胺对小鼠疼痛感受的影响<英文>

作     者：Anna CAPASSO,Alberto LOIZZO 

作者机构：Department of Pharmaceutical Sciences University of Salerno Via Ponte Don Melillo 84084 Fisciano Salerno Istituto Superiore di Sanita viale Regina Elena 299 00161 Roma Italy 

出 版 物：《Acta Pharmacologica Sinica》 (中国药理学报(英文版))

年 卷 期：2001年第22卷第7期

页      面：29-34页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1006[医学-中西医结合] 100706[医学-药理学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：半胱胺 疼痛测定 镇痛药 

摘      要：INTRODUCTION Cysteamine (β-mercaptoethylamine) is a thiol com-pound whose biological activities have recently receivedgreat attention, and that can be found in animals whenacetyl coenzyme A is hydrolized by *** it has been used in the treatment ofacetaminophen poisoning and in the treatment ofnephropathic cystinosis. It was reported that cys-teamine depletes somatostatin in the stomach, duodenum,pancreas, gut and hypothalamus of rat. Cysteaminewas also found to deplete somatostatin in the brain