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Role of multi-detector computed tomography for biliary complications after liver transplantation

Role of multi-detector computed tomography for biliary complications after liver transplantation

作     者:Xiao-Chun Meng Wen-Sou Huang Pei-Yi Xie Xiu-Zhen Chen Ming-Yue Cai Hong Shan Kang-Shun Zhu 

作者机构:Department of Radiology the Third Affiliated Hospital Sun Yat-Sen University 

出 版 物:《World Journal of Gastroenterology》 (世界胃肠病学杂志(英文版))

年 卷 期:2014年第20卷第33期

页      面:11856-11864页

核心收录:

学科分类:1002[医学-临床医学] 10[医学] 

基  金:Supported by National Natural Science Foundation of China,No.81201090,No.81371655 Guangdong Natural Science Foundation,No.S2012010008367 

主  题:Liver Transplantation Biliary Complica-tions Compu 

摘      要:AIM: To investigate the diagnostic performance of multi-detector computed tomography(MDCT) in detecting biliary complications after orthotopic liver transplantation(OLT). METHODS: Eighty-three consecutive OLT recipients, who presented with clinical or biochemical signs of biliary complications, underwent MDCT examination. Two experienced radiologists assessed MDCT images in consensus to determine biliary complications. Final confirmation was based on percutaneous transhepatic cholangiography or endoscopic retrograde cholangiography in 58 patients, surgery in four patients, liver biopsy in 10, and clinical and sonography follow-up in 11 patients. RESULTS: Biliary complications were eventually confirmed in 62 of 83 patients(74.7%), including anastomotic biliary strictures in 32, nonanastomotic biliarystrictures in 21, biliary stones in nine(5 with biliary strictures), anastomotic bile leak in five, and biloma in six(all with nonanastomotic strictures, and 2 with biligenic hepatic abscess). Twenty-one patients had no detection of biliary complications. The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of MDCT for detecting biliary strictures were 90.6%, 86.7%, 89.2%, 92.3% and 83.9%, respectively. For detecting biliary stones, anastomotic bile leak and biloma, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of MDCT were all 100%.CONCLUSION: MDCT is a useful screening tool for detecting biliary complications after OLT.

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