Synthesis of phenol-class azo derivatives of 4-aminosalicylic acid

作     者：Shi Fei Sheng Hui Xia Zheng Jiang Liu Zheng Bao Zhao 

作者机构：School of Pharmaceutical ScienceShanxi Medical UniversityTaiyuan 030001China First Clinical CollegeShanxi Medical UniversityTaiyuan 030001China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2008年第19卷第4期

页      面：419-422页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 100701[医学-药物化学] 10[医学] 

主　　题：4-Aminosalicylic acid Azo derivatives of 4-aminosalicylic acid Inflammatory bowel disease 

摘      要：To explore the better prodrug of 4-aminosalicylic acid（4-ASA）with higher activity and less side effects against the inflammatory bowel disease.4-ASA,after a succession of synthesis process,was conjugated with various carder molecules to get seven azo derivatives of *** compounds were characterized by FT-IR,^1H NMR,^13C NMR spectras in *** derivatives of 4-ASA were definituded.