Investigation of the Interaction Between Sodium (meta) Arsenite and Catechin via ESI Tandem Mass Spectrometry

作     者：CUI Sheng-yun WEN Jin-feng KIM Seung-jin LEE Yong-ill 

作者机构：Department of Chemistry School of Science Key Laboratory of Organism Functional Factors of the Changbai Mountain Ministry of Education Yanbian University Yanji 133002 P. R. China Department of Chemistry Changwon National University Changwon 641-773 Korea 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2007年第23卷第5期

页      面：524-529页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 070301[理学-无机化学] 

基　　金：Supported by Korean Research Foundation(No.KRF-C00183) 

主　　题：Arsenic Catechin Detoxification ESI mass spectrometry 

摘      要：Catechin,one of the main components of green tea,is considered to have the remedy effect of arsenic poison,although the chemical mechanism is not well *** this study,sodium（meta）selenite,which is used as herbicide and insecticide as well as rodenticide,was simply mixed with catechin in the CH3OH/H2O（volume ratio 50∶50）solution to investigate the interaction between toxic inorganic arsenic compound and catechin via ESI tandem mass *** interaction products of mono-methylated arsenic with catechin in the presence of methanol were identified in the negative *** induced dissociation（CID）mass spectrometric measurements indicate that monomethylated arsenic was ＂alkylated＂ strongly by conjugation at the sites of C2＇ and C5＇ in the phenyl ring B of the *** interaction mechanism between sodium（meta）arsenite and catechin was *** results provide useful information to understand the chemical pathway of the detoxification of the arsenic toxicity by catechin.