Total Synthesis of (±)-Calanolide A and Its Anti-HIV Activity

作     者：Chun Mei ZHOU Lin WANG Ming Long ZHANG Zhi Zhong ZHAO (Institute of Materia Medica, Peking Union Medical College &Chinese Academy of Medical Sciences, Beijing 100050)Xing Quan ZHANG Xiang Hong CHEN Hong Shan CHEN (Institute of Medicinal Biotechno 

作者机构：Institute of Materia Medica Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100050 China Institute of Medicinal Biotechnology Peking Union Medical College Chinese Academy of Medical Sciences Beijing 100050 China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：1998年第9卷第5期

页      面：433-434页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

主　　题：total synthesis (±)-calanolide A anti-HIV activity 

摘      要：Anti-HIV agent (±)-calanolide A has been synthesized by a four-step approach startingfrom phloroglucinol, including the Pechmann reaction, Friedel-Crafts acylation, cyclization,chromenylation and Luche reduction.