Predictors of double balloon endoscopy outcomes in the evaluation of gastrointestinal bleeding

作     者：Hisham Hussan Nicholas R Crews Caroline M Geremakis Soubhi Bahna Jennifer L LaBundy Christine Hachem 

作者机构：Section of Intestinal Neoplasia and Hereditary Polyposis(INHP)Department of GastroenterologyHepatology and NutritionThe Ohio State University Medical Center Division of Gastroenterology and HepatologySaint Louis University School of Medicine School of MedicineSaint Louis University School of Medicine Center for Outcomes ResearchSaint Louis University Department of Internal MedicineSaint Louis University School of Medicine 

出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)

年 卷 期：2014年第6卷第6期

页      面：248-253页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Double balloon endoscopy Enteroscopy Obscure gastrointestinal bleeding Small bowel Anemia Arteriovenous malformations Arteriovenous malformations 

摘      要：AIM:To identify patients characteristics associated with double balloon endoscopy(DBE)outcomes in investigation of obscure gastrointestinal bleeding(OGIB).METHODS:Retrospective study performed at an academic tertiary referral *** endpoints were clinical factors associated with no diagnostic yield or non-therapeutic intervention of DBE performed for OGIB ***:We included fifty-five DBE between August 2010 and April *** mean age of the sample was 67 with 32 males(58.2%).Twenty-four DBE had no diagnostic yield and 30 DBE did not require ***-diagnostic yield was associated with performing two or more DBE studies in one day [odds ratio(OR):13.72,P=0.008],absence of blood transfusions within a year of the DBE(OR:7.16,P=0.03)and absence of ulcers or arteriovenous malformations(AVMs)on prior esophagogastroduodenoscopy(EGD)or colonoscopy(OR:19.30,P=0.033).Non-therapeutic DBE was associated with performing two or more DBE per day(OR:18.579,P=0.007),gastrointestinal bleeding episode within a week of the DBE(OR:11.48,P=0.003),fewer blood transfusion requirements prior to DBE(OR:4.55,P=0.036)and absence of ulcers or AVMs on prior EGD or colonoscopy(OR:8.47,P=0.027).CONCLUSION:Predictors of DBE yield and therapeutic intervention on DBE include blood transfusion requirements,previous endoscopic findings and possibly endoscopist fatigue.