Clinical features of coronary artery ectasia in the elderly
Clinical features of coronary artery ectasia in the elderly作者机构:Division of Dyslipidemia State Key Laboratory of Cardiovascular Disease Fu Wai Hospital National Center for Cardiovascular Diseases Chinese Academy of Medical Sciences Peking Union Medical College BeiLiShi Road 167 Beijing 100037 China Department of Cardiology Institute of Cardiovascular Diseases the First Affiliated Hospital Guangxi Medical University Nanning Guangxi 530021 China
出 版 物:《Journal of Geriatric Cardiology》 (老年心脏病学杂志(英文版))
年 卷 期:2014年第11卷第3期
页 面:185-191页
核心收录:
学科分类:090603[农学-临床兽医学] 0831[工学-生物医学工程(可授工学、理学、医学学位)] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 09[农学] 0906[农学-兽医学] 10[医学]
基 金:This article is partly supported by National Natural Sci-entific Foundation Specialized Re-search Fund for the Doctoral Program of Higher Education of China Fund of Capital Special Founda-tion of Clinical Application Research Capital Health Development Fund Bei-jing Natural Science Foundation (7131014) awarded to Dr. Jian-Jun Li
主 题:Coronary artery ectasia Elderly patients Clinical feature
摘 要:Objective To investigate the incidence, imaging and clinical characteristics in elderly patients with coronary artery ectasia (CAE). Methods A retrospective analysis was conducted on patients with CAE who underwent coronary angiography between January 2006 and December 2012. According to age, the enrolled patients were divided into two groups (elderly group, age≥ 65 years; non-elderly group, age 〈 65 years). The clinical feature, imaging characteristics and the 5-year survival rate of the two groups were *** The preva-lence of CAE in elderly patients was 0.33%. Patients in elderly group were found to have significantly higher proportion of female (30.1%vs. 10.1%,P〈 0.001), three-vessel disease (60.5%vs. 45.2%,P = 0.003) and localized ectasia (55.0%vs. 40.2%,P = 0.003). In addition, body mass index (20.90 ± 2.71 kg/m2vs. 22.31 ± 2.98 kg/m2,P 〈 0.001) and percentage of current smokers (45.0%vs. 64.6%,P 〈 0.001) were significantly lower in elderly group. Cumulative survival curves demonstrated reduced 5-year cumulative survival at the follow-up in the elderly group compared with the non-elderly group (88.0%vs. 96.0%,P = 0.002). But the 5-year event free survival rate failed to show a significant difference between the two groups (31.0%vs. 35.0%,P= 0.311).ConclusionThe prevalence of CAE in elderly patients was 0.33%, which was about 1/3 of the entire numbers of CAE patients. There were significant differences between the elderly and the non-elderly patients with CAE in terms of coronary artery disease risk factors and coronary artery ectatic characteristics. CAE might be asso-ciated with increased mortality risk in the elderly.