Clinical application of oral contrast-enhanced ultrasound in evaluating the preoperative T staging of gastric cancer

作     者：Yu Liang Wan-Yi Jing Jun Song Qiu-Xin Wei Zhi-Qing Cai Juan Li Ping Wu Dong Wang Yi Ma 

作者机构：Department of UltrasoundSichuan Provincial People's HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 610072Sichuan ProvinceChina Department of PathologySichuan Provincial People's HospitalSchool of MedicineUniversity of Electronic Science and Technology of ChinaChengdu 610072Sichuan ProvinceChina 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文）)

年 卷 期：2024年第30卷第41期

页      面：4439-4448页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Gastrointestinal Subspecialty Group of the Department of Ultrasound Medicine at Sichuan Provincial People's Hospital 

主　　题：Gastric cancer Oral contrast-enhanced ultrasound Tumor-node-metastasis staging Noninvasive diagnosis and screening Clinical value 

摘      要：BACKGROUND Oral contrast-enhanced ultrasound(OCEUS)is widely used in the noninvasive diagnosis and screening of gastric cancer(GC)in *** To investigate the clinical application of OCEUS in evaluating the preoperative T staging of gastric *** OCEUS was performed before the operation,and standard ultrasound images were *** depth of infiltration of GC(T-stage)was evaluated according to the American Joint Committee on Cancer 8th edition of the tumor-nodemetastasis staging ***,with postoperative pathological staging as the gold standard reference,the sensitivity,specificity,negative predictive value,positive predictive value,and diagnostic value of OCEUS T staging were *** OCEUS achieved diagnostic accuracy rates of 76.6%(T1a),69.6%(T1b),62.7%(T2),60.8%(T3),88.0%(T4a),and 88.7%(T4b),with an average of 75.5%.Ultrasonic T staging sensitivity exceeded 62%,aside from T1b at 40.3%,while specificity was over 91%,except for T3 with 83.5%.The Youden index was above 60%,with T1b and T2 being *** T staging corresponded closely with pathology in T4b(kappa0.75)and moderately in T1a,T1b,T2,T3,and T4a(kappa 0.40-0.75),registering a concordance rate exceeding 84%.CONCLUSION OCEUS was effective,reliable,and accurate in diagnosing the preoperative T staging of *** a noninvasive diagnostic technique,OCEUS merits clinical popularization.