Effects of Repetitive TranscranialMagnetic Stimulation on Upper Extremity Function in Acute Stroke:A Meta-analysis and Systematic Review

作     者：Chenyang ZHENG Wenfu ZHANG Bao ZHANG 

作者机构：Department of Hydrotherapy and PhysiotherapyRehabilitationMedicine CenterTaihe HospitalHubei University of MedicineShiyan 434021China Department of Pediatric RehabilitationRehabilitation Medicine CenterTaihe HospitalHubei University of MedicineShiyan 434021China 

出 版 物：《Medicinal Plant》 (药用植物（英文）)

年 卷 期：2024年第15卷第5期

页      面：50-53页

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

主　　题：Acute stroke rTMS Upper extremity function Meta-analysis 

摘      要：[Objectives]To conduct a comprehensive examination of the evidence-based impact of repetitive transcranial magnetic stimulation(rTMS)on upper extremity functionality in patients with acute stroke.[Methods]A rigorous and systematic electronic search was conducted across the Medline,PubMed,and Web of Science databases,encompassing literature up to July 1,*** ensure the reliability of the in-cluded studies,an assessment of their risk of bias was conducted using RevMan 5.4 software,in accordance with the rigorous standards out-lined in the Cochrane Handbook for Systematic ***,we employed either the random-effects model or the fixed-effects model,depending on the heterogeneity of the data,to estimate the standardized mean difference(SMD)in outcomes,utilizing Stata 18.0 software for statistical analysis.[Results]Our review encompassed a total of five studies,involving 252 patients with acute *** pooled analysis of these studies revealed a statistically significant improvement in Fugl-Meyer Assessment of the Upper Extremity(FMA-UE)scores among pa-tients who received rTMS therapy(SMD=2.71,95%CI:0.85 to 4.56;P0.0001),albeit with considerable heterogeneity(I^(2)=97.65%)across the trials.[Conclusions]The results of this systematic review and meta-analysis underscore the promising potential of rTMS in enhancing upper extremity function in patients who have experienced an acute *** findings provide compelling evidence for the therapeutic benefits of rTMS in this patient population.