Retrospective cohort study on the postoperative survival rate enhancement of patients with colorectal cancer using three traditional Chinese medicine formulations:evidence from 1,361 cases

作     者：Kailong Zhao Xiaomin Su Wenwen Pang Yijia Wang Hongzhou Li Yi Zhang Leixin Jin Jun Xue Weizheng Liang Zhiqiang Feng Qiurong Han Yao Yao Tianyi Chen Qinghuai Zhang Xipeng Zhang Wenke Zheng Chunze Zhang Kailong Zhao;Xiaomin Su;Wenwen Pang;Yijia Wang;Hongzhou Li;Yi Zhang;Leixin Jin;Jun Xue;Weizheng Liang;Zhiqiang Feng;Qiurong Han;Yao Yao;Tianyi Chen;Qinghuai Zhang;Xipeng Zhang;Wenke Zheng;Chunze Zhang

作者机构：School of MedicineNankai UniversityTianjinChina Department of Colorectal SurgeryTianjin Union Medical CenterTianjinChina Department of ImmunologyNankai University School of MedicineNankai UniversityTianjinChina Department of Clinical LaboratoryTianjin Union Medical CenterTianjinChina Laboratory of Oncologic Molecular MedicineTianjin Union Medical CenterTianjinChina Department of GastroenterologyTianjin Union Medical CenterTianjinChina Tianjin Institute of ColoproctologyTianjinChina School of Integrative MedicineTianjin University of Traditional Chinese MedicineTianjinChina Department of General SurgeryThe First Affiliated Hospital of Hebei North UniversityZhangjiakouChina The Institute of Translational MedicineTianjin Union Medical CenterTianjinChina Evidence-based Medicine Center of the Institute of Traditional Chinese Medicine at Tianjin University of Traditional Chinese MedicineTianjinChina 

出 版 物：《Acupuncture and Herbal Medicine》 (针灸和草药（英文）)

年 卷 期：2024年第4卷第3期

页      面：399-404页

学科分类：1006[医学-中西医结合] 1005[医学-中医学] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by the Key Research Project of Tianjin Science and Technology Support Program(19YFZCSY00420) Tianjin Natural Science Foundation(21JCZDJC00060,21JCYBJC00180,and 21JCYBJC00340) Tianjin Key Medical Discipline Construction Project(TJYXZDXK-044A) Hospital Management Research Project of Tianjin Hospital Association(2019ZZ07) Beijing-Tianjin-Hebei Basic Research Cooperation Project(23JCZXJC00390) 

主　　题：Colorectal cancer Disease-free survival Traditional Chinese medicine Overall survival 

摘      要：Background:Prior studies have affirmed the safety and effectiveness of traditional Chinese medicine in treating colorectal cancer ***,definitive evidence regarding whether traditional Chinese medicine can significantly enhance the survival of colorectal cancer patients remains *** study seeks to provide conclusive insights by examining the postoperative administration of Xihuang capsules,Pingxiao capsules,and Zilongjin tablets and its impact on the 5-year overall survival(OS)and disease-free survival(DFS)rates among colorectal cancer ***:A retrospective study was conducted,involving 1,361 patients selected from the medical *** retrospective study was carried out at a medical center in Tianjin,*** assessed differences in postoperative OS and DFS between the control group and the medication group using Kaplan–Meier survival analysis and Cox proportional hazards ***,propensity score matching was used to mitigate imbalances in baseline characteristics among ***:Before propensity score matching,Xihuang capsules could prolong the 5-year OS(79.9%vs.81.4%,P=0.0480)and 5-year DFS(74.9%vs.79.5%,P=0.0046)of patients after *** conclusions were obtained after propensity score matching:OS(74.8%vs.78.3%,P=0.0084),DFS(72.7%vs.78.9%,P=0.008).Patients taking Pingxiao capsules showed improved 5-year OS(77.2%vs.84.0%,P=0.0383)and 5-year DFS(69.9%vs.80.0%,P=0.0157)after propensity score *** taking Zilongjin tablets showed improvement in the 2-year OS(84.2%vs.93.1%,P=0.0390)and 1-year DFS(88.2%vs.92.0%,P=0.0320)after propensity score ***:Xihuang capsules and Pingxiao capsules significantly improved the 5-year OS and DFS of patients with colorectal cancer after *** tablets showed improvement in the 2-year OS and 1-year DFS after surgery for patients.