Odor representation and coding by the mitral/tufted cells in the olfactory bulb

作     者：Panke WANG Shan LI An’an LI Panke WANG;Shan LI;An'an LI

作者机构：School of Biomedical EngineeringGuangdong Medical UniversityDongguan 523808China Jiangsu Key Laboratory of Brain Disease and BioinformationResearch Center for Biochemistry and Molecular BiologyXuzhou Medical UniversityXuzhou 221002China 

出 版 物：《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》 (浙江大学学报（英文版）B辑（生物医学与生物技术）)

年 卷 期：2024年第25卷第10期

页      面：824-840页

核心收录：

学科分类：0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 

基　　金：supported by the National Natural Science Foundation of China(Nos.32271055 and 32070995) the Jiangsu Province Innovative and Entrepreneurial Team Program,and the Guangdong Medical University(No.GDMUB2022048),China 

主　　题：Olfactory bulb Mitral/tufted cells Odor identity Neural representation Information encoding 

摘      要：The olfactory bulb(OB)is the first relay station in the olfactory system and functions as a crucial *** can represent odor information precisely and accurately in an ever-changing *** the only output neurons in the OB,mitral/tufted cells encode information such as odor identity and ***,the neural strategies and mechanisms underlying odor representation and encoding in the OB have been investigated *** we review the main progress on this *** first review the neurons and circuits involved in odor representation,including the different cell types in the OB and the neural circuits within and beyond the *** will then discuss how two different coding strategies—spatial coding and temporal coding—work in the rodent ***,we discuss potential future directions for this research ***,this review provides a comprehensive description of our current understanding of how odor information is represented and encoded by mitral/tufted cells in the OB.