Decoding the intracellular trafficking rule for circular RNAs
作者机构：Center for Molecular OncologyFrontiers Science Center for Disease-related Molecular NetworkState Key Laboratory of Biotherapy and Cancer CenterWest China HospitalSichuan University
出 版 物：《Science China Life Sciences》 (中国科学:生命科学(英文版))
年 卷 期：2024年
核心收录：
学科分类：0710[理学-生物学] 07[理学] 09[农学] 071007[理学-遗传学] 0901[农学-作物学] 090102[农学-作物遗传育种]
基 金：supported by the National Natural Science Foundation of China (82273168) the 1.3.5 Project for Disciplines of Excellence, West China Hospital of Sichuan University (ZYGD23027)
摘 要：Circular RNAs (circRNAs) are endogenous single-stranded RNAs with a covalently closed loop generated from‘backsplicing’of precursor mRNA (pre-mRNA)in the *** evidence emphasizes their significance in cellular homeostasis by serving as miRNA sponges,scaffolds for biomolecules,or templates for *** dysregulation has been implicated in human diseases,and clinical trials of circRNAs as potential biomarkers or therapeutic agents are ongoing.
同方期刊数据库