Attenuation correction for dedicated breast PET using only emission data based on consistency conditions

作     者：王璐 柴培 武丽伟 贠明凯 周小林 刘双全 张玉包 单保慈 魏龙 

作者机构：Key Laboratory of Nuclear Analysis TechniquesInstitute of High Energy PhysicsChinese Academy of Sciences Graduate University of Chinese Academy of Sciences Beijing Engineering Research Center of Radiographic Techniques and Equipment 

出 版 物：《Chinese Physics C》 (中国物理C（英文版）)

年 卷 期：2013年第37卷第1期

页      面：138-143页

核心收录：

学科分类：0907[农学-林学] 0709[理学-地质学] 090705[农学-野生动植物保护与利用] 09[农学] 0708[理学-地球物理学] 0804[工学-仪器科学与技术] 0827[工学-核科学与技术] 0703[理学-化学] 0704[理学-天文学] 0702[理学-物理学] 

基　　金：Supported by National Natural Science Foundation of China(81101070) 

主　　题：attenuation correction breast PET consistency conditions 

摘      要：Accurate attenuation correction is required in dedicated breast PET imaging systems for image artifact removal and quantitative studies. In this study, a method using only emission data based on consistency conditions is proposed for attenuation correction in breast PET imaging systems. The consistency conditions are exploited to evaluate the accuracy of the estimated attenuation distribution and find the appropriate parameters that yield the most consistent attenuation distribution with the measured emission data. We have proved the validity of the method with experimental investigations and single-patient studies using a dedicated breast PET. The results show that the method is capable of accurately estimating the attenuation distribution of a uniform attenuator from the experimental data with various relatively low activities. The results also show that in single-patient studies, the method is robust for the irregular boundary of breast tissue and provides a distinct improvement in image quality.