Synthesis and Complexation Properties of Novel Chiral Calix[4]-1,3-aza-crown and Calix[4]arene Hydrazone Derivative

作     者：YANG Fa-fu HUANG Zhi-sheng GUO Hong-yu HONG Bi-qiong ZHANG Xiao-yi 

作者机构：College of Chemistry and Materials Science Fujian Normal University Fuzhou 350007 P R. China Fujian Key Laboratory of Polymer Materials Fuzhou 350007 P. R. China 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2010年第26卷第4期

页      面：546-549页

核心收录：

学科分类：081702[工学-化学工艺] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Supported by the National Natural Science Foundation of China(No.20402002) Natural Science Foundation of Fujian Province,China(No.2009J01019) 

主　　题：Calixcrown Chiral Amino acid Hydrazone Extraction 

摘      要：Refluxing calix[4]-1,3-substituted benzaldehyde derivative（4） with glycine hydrazide derivative, we obtained a novel calix[4]arene hydrazone derivative（5） via ＂1＋2＂ condensation in a yield of 78%. In the reaction of compound 4 with L-leucine hydrazide derivative at room temperature, lariat calix[4]-1,3-aza-crown（6） with chiral amino acid group as branched chain was synthesized via ＂1＋ 1＂ addition in a yield of 70%. The preliminary extraction experiments suggested that hosting compounds 5 and 6 possessed good complexation abilities for a-amino acids.