Matching traditional Chinese medicine and western medicine-based research:Advanced nutraceutical development for proactive gastric cancer prevention
作者机构：Department of Biomolecular SciencesUniversity of Urbino Carlo BoUrbino 61029Italy Hong Kong Chinese Medicine Clinical Study CentreChinese EQUATOR CentreSchool of Chinese MedicineChinese Clinical Trial Registry(Hong Kong)Hong Kong Baptist UniversityHong Kong 999077China Centre for Chinese Herbal Medicine Drug DevelopmentHong Kong Baptist UniversityHong Kong 999077China Centre for Cancer and Inflammation ResearchSchool of Chinese MedicineHong Kong Baptist UniversityHong Kong 999077China Department of ChemistryCollege of ScienceSalahaddin University-ErbilErbil 44001Iraq Department of PharmacognosyFaculty PharmacyTishk International UniversityErbil 44001Iraq Institute of Oncology ResearchBellinzona CH6500Switzerland Universitàdella Svizzera ItalianaLugano CH6900Switzerland
出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)
年 卷 期：2024年第16卷第9期
页 面：3798-3819页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Traditional Chinese medicine Precision medicine Molecular network Phytochemistry Food chemistry Nutraceuticals Gastric cancer
摘 要：Gastric cancer(GC),the third leading cause of cancer-related death globally,is complex and *** review explores multidisciplinary investigations of traditional Chinese medicine(TCM)combined with Western medical practices,emphasizing the development of nutraceuticals for cancer *** advanced analytical chemistry and food chemistry techniques,this study investigated how TCM components may be optimized for nutraceutical *** on molecular interactions with GC pathways,particularly the NF-κB,PI3K/Akt,and Wnt/β-catenin pathways,we examined the effects of TCM polyherbal formulas,extracts,and isolated *** agents modulate apoptosis and cellular proliferation,underscoring their potential in preventive *** convergence of nutraceutical and medicine food homology studies highlights a significant shift towards integrating TCM-derived compounds in a preventive health *** approach aims not only to enhance efficacy and reduce side effects but also to champion a preventive paradigm using personalized medicine to advance proactive health maintenance and disease *** combination of TCM and western medical practices offers promising avenues for future research and practical applications in GC prevention.
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