Treatment of solitary gastric carcinoid tumor by endoscopic polypectomy in a patient with pernicious anemia

作     者：Gurhan Kadikoylu Irfan Yavasoglu Vahit Yukselen Esra Ozkara Zahit Bolaman 

作者机构：Internist HematologistAdnan Menderes University Medical FacultyDivision of HematologyAydinTurkey Internist Fellow in hematologyAdnan Menderes University Medical FacultyDivision of HematologyAydinTurkey Internist GastroenterologistAdnan Menderes University Medical FacultyDivision of GastroenterologyAydinTurkey Pathologist Adnan Menderes University Medical FacultyDivision of PathologyAydinTurkey 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2006年第12卷第26期

页      面：4267-4269页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Solitary Pernicious anemia Gastric carcinoid tumor Endoscopic polypectomy 

摘      要：Type I gastric cardnoid tumors result from hypergastrinemia in 1%-7% of patients with pernicious anemia. We diagnosed pernicious anemia in a 48-year-old female patient with complaint of fatigue for three months. She had no gastrointestinal symptoms. Endoscopic examination ot the upper gastrointestinal tract revealed atrophic gastritis and a polypoid lesion in the corpus of 3-4 mm in size. Endoscopic polypectomy was performed. Histopathological examination of the specimen revealed positive chromogranin A and synaptophysin stainings compatible with the diagnosis of a carcinoid tumor. Serum gastrin level was increased, urinary 5-hydroxyindoleacetic acid was within the normal range. There was no other symptom, sign, or laboratory finding of a carcinoid syndrome in the patient. No metastasis was found with indium-ill octreotide scan, computed tomographies of abdomen and thorax. Type I gastric carcinoid tumors are only rarely solitary and patients with tumors 〈 1 cm in size may benefit from endoscopic polypectomy.