Pain and immune function in patients undergoing gastric cancer surgery following stellate ganglion block with total intravenous anesthesia
作者机构：Department of AnesthesiologyThe Kunshan Second People’s HospitalKunshan 215300Jiangsu ProvinceChina
出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)
年 卷 期：2024年第16卷第9期
页 面：2961-2967页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：The Kunshan Social Development Science and Technology Special Project No.KS2241
主 题：Stellate ganglion block Total intravenous anesthesia Laparoscopy Radical gastric cancer surgery Immune
摘 要：BACKGROUND Stellate ganglion block is a commonly used sympathetic nerve block technique that restores the balance of the sympathetic and vagal nervous systems of the body and inhibits sympathetic nerve *** To analyze the effect of a stellate ganglion block combined with total diploma intravenous anesthesia on postoperative pain and immune function in patients undergoing laparoscopic radical gastric cancer(GC)surgery to provide a refe-rence basis for the formulation of anesthesia protocols for radical GC *** This study included 112 patients who underwent laparoscopic radical surgery for GC between January 2022 and March *** was no restriction on *** patient grouping method used was a digital random table method,and the num-ber of cases in each group was *** control group was administered total intravenous anesthesia,and the observation group compounded the stellate gan-glion block according to the total intravenous anesthesia *** hemodynamics,pain levels,and immune indices were compared between the *** The heart rate and mean arterial pressure in the observation group after in-tubation were lower than those in the control group(P0.05).The number of CD3+,CD4+,and CD4+/CD8+cells at the end of surgery was higher in the observation group than in the control group,and the number of CD8+cells was lower in the observation group than in the control group(P0.05).CONCLUSION The application of a stellate ganglion block combined with total intravenous anesthesia had no significant effect on postoperative pain levels in patients undergoing laparoscopic radical GC ***,it can safely reduce the effect of surgery on the immune function
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