Research progress in the phytochemistry and biology of Ilex pharmaceutical resources

作     者：Dacheng Hao Xiaojie Gua Peigen Xiao Zhanguo Liang Lijia Xu Yong Peng 

作者机构：Biotechnology InstituteSchool of Environmental and Chemical EngineeringDalian Jiaotong UniversityDalian 116028China Department of Metabolic BiologyJohn Innes CentreNorwich Research ParkNorwich NR47UHUK Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine of Ministry of EducationInstitute of Medicinal Plant DevelopmentChinese Academy of Medical SciencesBeijing 100193China 

出 版 物：《Acta Pharmaceutica Sinica B》 (药学学报（英文版）)

年 卷 期：2013年第3卷第1期

页      面：8-19页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：The study was funded by Dalian Jiaotong University and Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine,Ministry of Education,China This work is also supported by the National Natural Science Foundation of China(No.81274188) 

主　　题：Ilex Chemical components Pharmacology Chemotaxonomy Phylogeny Pharmaceutical and food resource 

摘      要：Ilex is a botanical source for various health-promoting and pharmaceutically active compounds that have been used in traditional Chinese medicine and food for thousands of *** interest in Ilex pharmaceutical and food resources has led to additional discoveries of terpenoids,saponins,polyphenols(especially flavonoids),glycosides,and many other compounds in various Ilex species,and to investigation of their chemotaxonomy,molecular phylogeny and *** continuation of our studies on Ilex pharmacology and phylogeny,we review the phytochemistry,chemotaxonomy,molecular biology and phylogeny of Ilex species and their relevance to health-promotion and therapeutic *** similarity and dissimilarity between Ilex paraguariensis,the source plant of mate tea,and the source plants of large-leaved K udingcha(e.g.,Ilex kudingcha and Ilex latifolia)are *** is essential to utilize emerging technologies in non-Camellia tea studies to promote the sustainable utilization of Ilex resources and the identification and development of novel compounds with potential health and clinical *** biology and -omicstechnologies will play an increasingly important role in pharmaceutical and food research on the bioactive compounds of Ilex species.