Additive Hazards Regression under Generalized Case-Cohort Sampling

作     者：Ji Chang YU Yue Yong SHI Qing Long YANG Yan Yan LIU 

作者机构：School of Mathematics and StatisticsWuhan University School of Statistics and MathematicsZhongnan University of Economics and Law 

出 版 物：《Acta Mathematica Sinica,English Series》 (数学学报（英文版）)

年 卷 期：2014年第30卷第2期

页      面：251-260页

核心收录：

学科分类：02[经济学] 0202[经济学-应用经济学] 020208[经济学-统计学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 0714[理学-统计学（可授理学、经济学学位）] 070103[理学-概率论与数理统计] 0701[理学-数学] 10[医学] 

基　　金：supported by the Fundamental Research Fund for the Central Universities supported by National Natural Science Foundation of China(Grant No.11301545) supported by National Natural Science Foundation of China(Grant No.11171263) 

主　　题：Generalized case-cohort pseudo-score function weighted estimating equation optimalallocation 

摘      要：Case-cohort design usually requires the disease rate to be low in large cohort study,although it has been extensively used in ***,the disease with high rate is frequently observed in many clinical *** such circumstances,it is desirable to consider a generalized case-cohort design,where only a fraction of cases are *** this article,we propose the inference procedure for the additive hazards regression under the generalized case-cohort *** properties of the proposed estimators for the regression coefcients are *** demonstrate the efectiveness of the generalized case-cohort sampling,we compare it with simple random sampling in terms of asymptotic relative ***,we derive the optimal allocation of the subsamples for the proposed *** fnite sample performance of the proposed method is evaluated through simulation studies.