Preliminary assessing no-surgical treatment response in bronchogenic carcinoma with three-phase contrast material-enhanced MRI

作     者：Shenjiang Li Xuefeng Cui Debin Liu Wenjie Liang Yan Zhu Wenjie Bi 

作者机构：Department of Imageology The Eighty-eighth Military Hospital Tai＇an 271000 China 

出 版 物：《The Chinese-German Journal of Clinical Oncology》 (中德临床肿瘤学杂志（英文版）)

年 卷 期：2010年第9卷第8期

页      面：444-447页

学科分类：1007[医学-药学(可授医学、理学学位)] 08[工学] 080203[工学-机械设计及理论] 0802[工学-机械工程] 10[医学] 

主　　题：bronchogenic carcinoma MRI image enhancement evaluation of curative effect 

摘      要：Objective:The aim of this study was to evaluate the efficacy of three-phase contrast material-enhanced MRI in assessing no-surgical treatment response in peripheral bronchogenic carcinoma ***:Twenty-two patients with bronchogenic carcinoma after no-surgical treatment underwent three-phase contrast material-enhanced *** scans were obtained at 25 s,120 s and 180 s respectively after nonionic contrast material was administrated via the antecubital vein at a rate of 2 mL/s by using an *** and postcontrast signal intensity on every scan was *** Height(PH) and Maximum Enhancement(Emax) were *** pattern was evaluated on the images obtained at 120 s and 180 s after injection of contrast ***:Precontrast signal intensity,postcontrast signal intensity at 120 s and 180 s were 478 ± 108,926 ± 209 and 1050 ± ***(571 ± 225) and Emax(119 ± 49) of bronchogenic carcinoma after no-surgical treatment were significantly lower than those of bronchogenic carcinoma without any therapy(mean PH 655,mean Emax 150)(t = 2.178,P = 0.005 0.05,t = 4.196,P = 0.001 0.05).Six cases among 22 appeared homogeneous enhancement at 180 *** 120 s,there were 4 cases with inhomogeneous enhancement,1 case with homogeneous enhancement,1 case with peripheral enhancement among the 6 ***:Bronchogenic carcinoma after no-surgical treatment shows a gradual increase to the PH after administration of contrast ***-phase contrast material-enhanced MRI can reflect the blood supply of bronchogenic carcinoma and might be effective approach for evaluation of no-surgical treatment response in bronchogenic carcinoma.