A report of 28 cases of 3-year follow-up after liver transplantation for advanced hepatocellular carcinoma

作     者：De-ChenWang Tong-LinZhang Shi-BingSong JiongYuan Dian-RongXiu Xiao-XiaYang 

作者机构：DepartmentofGeneralSurgeryPekingUniversityThirdHospitalBeijing100083China 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2004年第10卷第14期

页      面：2134-2135页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：病例报告 肝移植 跟踪报告 肝细胞癌 肿瘤 

摘      要：AIM: To investigate the therapeutic value of liver transplantation for advanced hepatocellular cardnoma (HCC). METHODS: Twenty-eight patients with advanced HCC were treated by liver transplantation from August 2000 to October 2003 at Peking University Third hospital. All the patients were followed up to evaluate the ***: The longest follow-up duration was 3 years and 3 mo. Till the end of the follow-up period, 17 patients had already died and 11 were alive. Of those who died, 10 patients died of tumor recurrence, 4 died during the perioperative period, 2 died of variceal bleeding, and 1 died of biliary complication. According to life table method, the 1-, 2-, and 3-year survival rates were 87.5%, 52.5%,and 42.9%,respectively. CONCLUSION: Liver transplantation provides a new treatment under the circumstance of lacking of an effective treatment for advanced HCC at present. Some patients can survive for a relatively long time free of tumor. In our country,if the patients can afford liver transplantation, advanced HCC without extrahepatic metastasis is an indication for liver transplantation at present.