Simultaneous pancreas-kidney transplantation in a single center： 10-year retrospective analysis

作     者：ZHENG Jian-ming SONG Wen-li TU Jin-peng FENG Gang MO Chun-bai SHEN Zhong-yang 

作者机构：Department of Transplantation Tianjin First Central Hospital Tianjin 300192 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2011年第124卷第5期

页      面：683-686页

核心收录：

学科分类：090801[农学-水产养殖] 082802[工学-农业水土工程] 1002[医学-临床医学] 0908[农学-水产] 08[工学] 0828[工学-农业工程] 09[农学] 0815[工学-水利工程] 0903[农学-农业资源与环境] 

主　　题：simultaneous pancreas-kidney transplantation diabetes mellitus, end-stage renal disease 

摘      要：Background Simultaneous pancreas-kidney transplantation （SPKT） is the best treatment option for diabetic patients with advanced chronic renal failure. The current study aimed to analyze the surgical indications, treatments and prognosis of *** We retrospectively analyzed 40 cases of SPKT performed between December 1999 and January 2010 in our center, including the survival rate, complications and the reasons of *** Of all the 40 SPKT cases, the one-year survival rates of the recipients, kidney and pancreas transplant graft were 97.6%, 97.6% and 92.7%, while 97.6%, 91.1%, 92.7% at 3 years and 83.6%, 78.0%, 79.4% at 5 years, respectively. After SPKT, 10 patients need reoperation because of surgical complications （14 operations）. The reoperation rate was 25%, including 2 patients （4 operations） with hematuria, 4 patients with abdominal hemorrhage, 2 patients （3 operations） with abdominal infection, 1 patient with pancreatic venous thrombosis, 1 patient with anastomotic leakage, and 1 patient with *** Although SPKT provides a successful and effective treatment for diabetics with end-stage renal disease, how to reduce the complications of this treatment still need further effort.