Ligation-assisted endoscopic submucosal resection following unroofing technique for small esophageal subepithelial lesions originating from the muscularis propria

作     者：Quan Lu Quan-Zhou Peng Jun Yao Li-Sheng Wang De-Feng Li 

作者机构：Department of GastroenterologyShenzhen People’s HospitalShenzhen 518020Guangdong ProvinceChina Department of PathologyShenzhen People’s HospitalShenzhen 518020Guangdong ProvinceChina Department of GastroenterologyShenzhen People’s HospitalThe Second Clinical Medical CollegeJinan UniversityShenzhen 518020Guangdong ProvinceChina The First Affiliated HospitalSouthern University of Science and TechnologyShenzhen 518020Guangdong ProvinceChina 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2024年第30卷第32期

页      面：3748-3754页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by the Engineering Training Funds in Shenzhen,No.SYLY201718,No.SYJY201714,and No.SYLY201801 Technical Research and Development Project of Shenzhen,No.JCYC20170307100911479,No.JCYJ20190807145617113,No.JCYJ20210324113802006 

主　　题：Subepithelial lesions Muscularis propria Esophagus Ligation Endoscopic submucosal resection 

摘      要：BACKGROUND The majority of esophageal subepithelial lesions originating from the muscularis propria(SEL-MPs)are benign in nature,although a subset may exhibit malignant *** endoscopic resection techniques are time-consuming and lack efficacy for small *** To evaluate the efficacy and safety of ligation-assisted endoscopic submucosal resection(ESMR-L)following unroofing technique for small esophageal *** From January 2021 to September 2023,17 patients diagnosed with esophageal SEL-MPs underwent ESMR-L following unroofing technique at the endoscopy center of Shenzhen People’s *** of clinicopathological characteristics and clinical outcomes were collected and *** The mean age of the patients was 50.12±12.65 *** mean size of the tumors was 7.47±2.83 mm and all cases achieved en bloc resection *** average operation time was 12.2 minutes without any *** identified 2 Lesions(11.8%)as gastrointestinal stromal tumors at very low risk,12 Lesions(70.6%)as leiomyoma and 3 Lesions(17.6%)as smooth muscle *** recurrence was found during the mean follow-up duration of 14.18±9.62 *** ESMR-L following roofing technique is an effective and safe technique for management of esophageal SEL-MPs smaller than 20 mm,but it cannot ensure en bloc resection and may require further treatment.