Senolystics from natural products for extending health and lifespan
作者机构：School of RadiologyShandong First Medical University&Shandong Academy of Medical SciencesTai’an 271016China Medical Science and Technology Innovation CenterShandong First Medical University&Shandong Academy of Medical SciencesJinan 250062China Key Laboratory of Flexible Electronics and Institute of Advanced MaterialsSchool of Physical and Mathematical SciencesNanjing Tech UniversityNanjing 211816China.
出 版 物：《Traditional Medicine Research》 (TMR传统医学研究)
年 卷 期：2024年第9卷第11期
页 面：76-77页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by Shandong Provincial Natural Science Foundation General Program(ZR2022MH226)
主 题：irreversible holds aging
摘 要：Senescence,a multifaceted cellular process,intricately regulates organismal aging by imposing irreversible growth arrest on *** phenomenon,characterized by altered gene expression and the accumulation of senescent cells,significantly contributes to age-related physiological decline and the onset of various age-associated pathologies[1].Cellular senescence,the irreversible cessation of cell division,is intricately linked to the aging process in individuals[2].As organisms age,the accumulation of senescent cells increases,contributing to tissue dysfunction and the development of age-related *** the mechanisms underlying cellular senescence holds promise for elucidating the fundamental processes governing aging and may pave the way for targeted interventions to mitigate age-associated decline[3].
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