Relation between eardrum flap area and healing outcome of traumatic eardrum perforation

作     者：LOU Zheng-cai TANG Yong-mei WU Xiao-hong CHEN Jia-hai 

作者机构：Department of Otorhinolaryngology Yiwu Central Hospital Yiwu 322000 Zhejiang Province China 

出 版 物：《Chinese Journal of Traumatology》 (中华创伤杂志（英文版）)

年 卷 期：2011年第14卷第5期

页      面：264-268页

学科分类：090603[农学-临床兽医学] 0403[教育学-体育学] 1002[医学-临床医学] 08[工学] 09[农学] 0906[农学-兽医学] 080401[工学-精密仪器及机械] 0804[工学-仪器科学与技术] 081102[工学-检测技术与自动化装置] 0811[工学-控制科学与工程] 

基　　金：Science and Technology Agency of Zhejiang Province  (2009C33097) 

主　　题：Tympanic membraneperforation Wounds and injuries Surgical flaps Gelatin sponge, absorbable 

摘      要：Objective： To retrospectively study the clinical effects of eardrum flap area on the healing outcome following traumatic ***： Totally 291 traumatic eardrum perforations with in-/everted edges were included in this study. They were randomly divided into three groups and received conservative treatment, epidermal growth factor （EGF） via Gelfoam patching, or edge-approximation plus Gelfoam patching respectively. Patients in each group were further divided into two subgroups according to the eardrum flap area ≤ 1/2 or 〉1/2 of the perforation size. The healing rate and mean closure time after tympanic membrane perforation were evaluated at three ***： Of the total 291 participants, 281 were included in the final statistical analysis. The area of curled edge did not affect the healing outcome significantly in any groups （P〉0.05）. The healing rate varied slightly： 90.7% vs 92.3% in spontaneous healing group, 98.2% vs 97.4% in EGF via Gelfoam patching group, and 96.5% vs 100% in edge-approximation plus Gelfoam patching group. In addition, in all groups the area of curled edge did not affect the mean closure time significantly （P〉0.05）. The closure time was （32.3±2.4） d vs （30.6±3.1） d in sponaneous healing group, （13.4±2.5） d vs （13.1± 1.9） d in EGF via Gelfoam patching group, and （11.9±3.1） d vs （12.2±2.1） d in edge-approximation plus Gelfoam patching ***： The eardrum flap area of traumatic eardrum perforation does not significantly affect the clinical outcomes.