Orthogonal design to sift the optimal parameter of Neiguan acupuncture for cerebral infarction

作     者：Yanan Zhang Sha Yang Xiaonong Fan Shu Wang Nina He Lingxin Li Ding Luo Xuemin Shi 

作者机构：First Teaching Hospital of Tianjin University of Traditional Chinese Medicine Acupuncture and Moxibustion Research Institute of Tianjin University of Traditional Chinese Medicine Key Laboratory of Cerebropathy Acupuncture Therapy of State Administration of Traditional Chinese Medicine Tianjin Key Laboratory of Acupuncture & Moxibustion Science Three-level Laboratory of Acupuncture Dose-Effect RelationshipState Administration of Traditional Chinese Medicine Wuhai Hospital of Traditional Chinese Medicine Department of Rehabilitation MedicineWest China Medical SchoolWest China Hospital Sichuan University Postgraduate SchoolTianjin University of Traditional Chinese Medicine 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2013年第8卷第28期

页      面：2641-2648页

核心收录：

学科分类：0710[理学-生物学] 1005[医学-中医学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100512[医学-针灸推拿学] 10[医学] 

基　　金：funded by Development Plan(973 Plan) of National Critical and Basic Research No.2012CB518505 2010CB530500 2006CB504504 

主　　题：neural regeneration acupoint quantified acupuncture Neiguan middle artery occlusion injury lift-ing and thrusting method orthogonal design lifting and thrusting frequency acupuncture duration grants-supported paper neuroregeneration 

摘      要：The individual difference and non-repeatability in acupuncture have not only restricted the devel- opment of acupuncture, but have also affected the specificity of acupoints. The present study used instruments to control needle depth, lifting and thrusting frequency, and the duration of acupuncture. Effects of the quantified acupuncture were observed at Neiguan （PC6） with different stimulation parameters. A frequency of 1, 2, or 3 Hz and duration of 5, 60, or 180 seconds were used to observe cerebral blood flow and ratio of infarct volume recovery. Results showed that stimulation at Neiguan with a frequency of 1 Hz and long duration of 180 seconds or 2/3 Hz and long duration of 5/60 seconds significantly increased cerebral blood flow and decreased the ratio of infarct volume. In- teractions between frequency and duration play a critical role in quantified acupuncture therapy.